INT255660

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Rgc32) cytoskeleton (Rgc32) nucleus (Rgc32)
cell cycle (Rgc32) microtubule organizing center (Rgc32) cytoplasm (Rgc32)
Coq10a (Rattus norvegicus)
Rgc32 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 98.28 Very High Very High Very High
Glutamate 34 96.76 Very High Very High Very High
imagery 13 67.84 Quite High
antagonist 6 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 49 99.96 Very High Very High Very High
Cv Unclassified Under Development 1 98.28 Very High Very High Very High
Stress 1 97.96 Very High Very High Very High
Parkinson's Disease 1 95.24 Very High Very High Very High
Death 17 90.24 High High
Neurodegenerative Disease 4 84.00 Quite High
Glaucoma 56 78.48 Quite High
Ocular Hypertension 15 63.20 Quite High
Disease 16 26.92 Quite Low
Toxicity 3 12.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CoQ10 has been shown to prevent RGC apoptosis in a pressure-induced transient ischemia model by minimizing synaptic glutamate increase and inhibiting the MPTP formation (Nucci et al., 2007).
CoQ10 Negative_regulation (prevent) of RGC associated with parkinson's disease, glutamate, ischemia and apoptosis
1) Confidence 0.02 Published 2008 Journal Progress in Brain Research Section Body Doc Link PMC2603274 Disease Relevance 1.11 Pain Relevance 0.13

General Comments

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