INT256399

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ND4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 40.28 Quite Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leber Hereditary Optic Atrophy 48 98.56 Very High Very High Very High
Disease 9 95.16 Very High Very High Very High
Mitochondrial Disorders 1 88.64 High High
Growth Problems 1 86.48 High High
Intellectual Impairment 1 85.76 High High
Dystonia 1 84.04 Quite High
Muscle Weakness 1 83.32 Quite High
Ganglion Cysts 5 69.48 Quite High
Atrophy 1 52.24 Quite High
Scotoma 1 41.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Initial molecular characterization of LHON revealed a G to A transition at nucleotide 11,778 in mtDNA in the gene specifying the NADH dehydrogenase subunit 4 (ND4) of complex I, resulting in an arginine to histidine substitution at amino acid 340 [13].
Positive_regulation (specifying) of dehydrogenase subunit 4 associated with leber hereditary optic atrophy
1) Confidence 0.01 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2605731 Disease Relevance 1.36 Pain Relevance 0

General Comments

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