INT256587

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.69
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ALB, TTR) cytoplasm (ALB, TTR) extracellular space (ALB, TTR)
extracellular region (ALB, TTR) small molecule metabolic process (ALB) enzyme binding (ALB)
Anatomy Link Frequency
plasma 2
ALB (Homo sapiens)
TTR (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 18 9.52 Low Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 91.92 High High
Toxicity 2 90.36 High High
Familial Amyloidotic Polyneuropathy 8 90.32 High High
Alzheimer's Dementia 26 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Amyloidosis 12 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This is specially crucial in this case because very strong plasma protein competitors of TTR include thyroid binding globulin (TBG), which has an order of magnitude high affinity for thyroxine [60], and albumin (ALB) which is at concentrations of two orders of magnitude higher than TTR in plasma.
ALB Binding (higher) of TTR in plasma
1) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2607018 Disease Relevance 0.35 Pain Relevance 0
This is specially crucial in this case because very strong plasma protein competitors of TTR include thyroid binding globulin (TBG), which has an order of magnitude high affinity for thyroxine [60], and albumin (ALB) which is at concentrations of two orders of magnitude higher than TTR in plasma.
albumin Binding (higher) of TTR in plasma
2) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2607018 Disease Relevance 0.35 Pain Relevance 0

General Comments

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