INT256854

Context Info Confidence 0.06 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0.08

cell differentiation (Tp63) nucleoplasm (Tp63) anatomical structure formation involved in morphogenesis (Tp63) Golgi apparatus (Tp63) nucleolus (Tp63) nucleus (Tp63)

Tp63 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Glutamate 1 83.76 cytokine 4 70.64 Bile 3 5.00 Inflammation 2 5.00 metalloproteinase 2 5.00 Hippocampus 2 5.00 anesthesia 1 5.00 isoflurane 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Stress 9 63.92 Shock 7 5.00 Adhesions 2 5.00 INFLAMMATION 2 5.00 Apoptosis 2 5.00 Hypersensitivity 2 5.00 Death 1 5.00 Decapitation 1 5.00 Cognitive Disorder 1 5.00 Male Breast Neoplasms 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The HFG male unique up-regulated pathways showed a strong presence of certain physiological functions, i.e. energy regulation/metabolism (Bile_acid, Butanoate, FA biosynth, Glyoxylate, KET, Propanoate, electronstranport, etc, glycolysis), immune regulation (par1, tob1), cell signaling (akap96, akapCentrosome) and steroid receptor activity (ANDROGEN, mta3).

Regulation (regulation) of KET

1) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2607546 Disease Relevance 0.06 Pain Relevance 0.08

General Comments

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