INT257478

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 9
Total Number 12
Disease Relevance 2.50
Pain Relevance 2.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
upper arm 2
liver 1
arm 1
hindlimb 1
elbow 1
Is(HSR;1)1Icg (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 648 100.00 Very High Very High Very High
ketamine 8 99.48 Very High Very High Very High
anesthesia 16 99.18 Very High Very High Very High
ischemia 44 98.56 Very High Very High Very High
isoflurane 8 90.60 High High
Bile 4 23.28 Low Low
Buprenorphine 8 5.16 Low Low
Pain 12 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphedema 196 99.80 Very High Very High Very High
Cv Unclassified Under Development 44 98.56 Very High Very High Very High
Increased Venous Pressure Under Development 32 81.72 Quite High
Toxicity 4 30.00 Quite Low
Necrosis 168 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Breast Cancer 12 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Pain 12 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vascular input function (VIF) of ICG in normal tissues has been described as a uniexponential function of ICG excretion by the liver because liver dynamics dominate ICG excretion [16].
Gene_expression (excretion) of ICG in liver
1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2626246 Disease Relevance 0 Pain Relevance 0.13
For time-series ICG imaging, mice under ketamine–xylazine anesthesia were injected with an intravenous bolus injection of ICG (0.1 mL of 400 µmol/L; Sigma, St.
Gene_expression (injection) of ICG associated with anesthesia, ketamine and imagery
2) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2626246 Disease Relevance 0.06 Pain Relevance 0.51
Time-series NIR fluorescence images were obtained after injecting ICG intravenously in a murine hindlimb ischemia model.
Gene_expression (injecting) of ICG in hindlimb associated with ischemia
3) Confidence 0.22 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2626246 Disease Relevance 0.18 Pain Relevance 0.14
For time-series ICG imaging, mice under ketamine–xylazine anesthesia were injected with an intravenous bolus injection of ICG (0.1 mL of 400 µmol/L; Sigma, St.
Gene_expression (imaging) of ICG associated with anesthesia, ketamine and imagery
4) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2626246 Disease Relevance 0.06 Pain Relevance 0.59
In rats of the control group A, OI images showed only a minimal and diffuse signal enhancement of paravertebral soft tissue after intravenous injection of both administered ICG doses. ?
Gene_expression (doses.) of ICG associated with imagery
5) Confidence 0.08 Published 2008 Journal J Transl Med Section Body Doc Link PMC2613387 Disease Relevance 0 Pain Relevance 0.09
Comparisons between animals injected with different ICG doses
Gene_expression (doses) of ICG
6) Confidence 0.08 Published 2008 Journal J Transl Med Section Body Doc Link PMC2613387 Disease Relevance 0 Pain Relevance 0.08
In rats of the control group A, OI images showed only a minimal and diffuse signal enhancement of paravertebral soft tissue after intravenous injection of both administered ICG doses. ?
Gene_expression (injection) of ICG associated with imagery
7) Confidence 0.08 Published 2008 Journal J Transl Med Section Body Doc Link PMC2613387 Disease Relevance 0 Pain Relevance 0.09
For detection of ICG fluorescence, the excitation filter was set at 755 nm, the emission filter was set at 830 nm.
Gene_expression (detection) of ICG
8) Confidence 0.07 Published 2008 Journal J Transl Med Section Body Doc Link PMC2613387 Disease Relevance 0 Pain Relevance 0.61
In two subjects, BCRL 4 and 5, ICG is not present above the elbow pre-treatment (A and B, respectively), whereas the ICG has advanced past the elbow and into the upper arm post-treatment (D and E).
Neg (not) Gene_expression (present) of ICG in upper arm associated with lymphedema
9) Confidence 0.01 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3005162 Disease Relevance 0.52 Pain Relevance 0
Before treatment, ICG was present in two subjects up to the elbow (5A and 5B); after treatment, the ICG travelled proximally above the elbow into the upper arm (5D and 5E).
Gene_expression (present) of ICG in elbow
10) Confidence 0.01 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3005162 Disease Relevance 0.54 Pain Relevance 0
Pre-treatment, ICG fluorescence was not detected in the shoulder or lateral upper arm of any subjects in the study.
Neg (not) Gene_expression (detected) of ICG in upper arm
11) Confidence 0.01 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3005162 Disease Relevance 0.61 Pain Relevance 0
In another subject, BCRL 6, prior to treatment (C), the ICG is present only at the injection site, and after treatment (F), the ICG has spread proximally through the arm. presents pre- (A, B, C) and post- (D, E, F) treatment images from three BCRL subjects.
Gene_expression (present) of ICG in arm associated with lymphedema
12) Confidence 0.01 Published 2010 Journal Biomedical Optics Express Section Body Doc Link PMC3005162 Disease Relevance 0.52 Pain Relevance 0

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