INT257861

From wiki-pain
Revision as of 03:24, 23 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.90
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mtor) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) nucleus (Mtor) kinase activity (Mtor)
Anatomy Link Frequency
hypothalamus 4
Mtor (Rattus norvegicus)
Pain Link Frequency Relevance Heat
palliative 3 96.08 Very High Very High Very High
long-term potentiation 9 58.48 Quite High
Hippocampus 27 55.60 Quite High
antagonist 11 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vasculitis 2 99.88 Very High Very High Very High
Injury 16 99.40 Very High Very High Very High
Neointima 11 90.28 High High
Disease Progression 6 78.60 Quite High
Renal Cancer 27 77.56 Quite High
Starvation 2 65.64 Quite High
Stress 3 63.32 Quite High
Fungal Infection 1 60.80 Quite High
Hyperplasia 4 60.64 Quite High
Aging 6 55.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In considering the role of local protein synthesis in synaptic plasticity underlying memory processing [21], [62], [63], the present results raise several questions: What are the upstream extracellular signals that mediate activation of mTOR signaling required for memory formation?
Positive_regulation (activation) of Gene_expression (signaling) of mTOR
1) Confidence 0.48 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0 Pain Relevance 0.09
In response to vascular injury, the expression of p-mTOR was increased after balloon injury due to proliferation of RAoSMCs.
Positive_regulation (increased) of Gene_expression (expression) of p-mTOR associated with injury and vasculitis
2) Confidence 0.32 Published 2008 Journal Yonsei Medical Journal Section Body Doc Link PMC2615285 Disease Relevance 0.50 Pain Relevance 0
Activation of hypothalamic mTOR or increased expression of S6K in the mediobasal hypothalamus results in decreased feeding [12], [32]; therefore, Sirt1 down-regulating S6K signaling fits our model on the regulation of energy balance by hypothalamic Sirt1.
Positive_regulation (Activation) of Gene_expression (expression) of mTOR in hypothalamus
3) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2790615 Disease Relevance 0.06 Pain Relevance 0
Activation of hypothalamic mTOR or increased expression of S6K in the mediobasal hypothalamus results in decreased feeding [12], [32]; therefore, Sirt1 down-regulating S6K signaling fits our model on the regulation of energy balance by hypothalamic Sirt1.
Positive_regulation (increased) of Gene_expression (expression) of mTOR in hypothalamus
4) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2790615 Disease Relevance 0.06 Pain Relevance 0
Discovery and development of rapamycin and rapalogs
Positive_regulation (Discovery) of Gene_expression (Discovery) of rapamycin
5) Confidence 0.14 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2880340 Disease Relevance 0.27 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox