INT25797

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Context Info
Confidence 0.09
First Reported 1980
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 5.14
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

OR2AL1P (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 1 99.16 Very High Very High Very High
Pain 5 98.16 Very High Very High Very High
headache 3 95.56 Very High Very High Very High
anticonvulsant 6 76.52 Quite High
Disease Link Frequency Relevance Heat
Pain 5 98.16 Very High Very High Very High
Renal Disease 1 97.08 Very High Very High Very High
Fever 2 96.80 Very High Very High Very High
Pressure And Volume Under Development 2 96.00 Very High Very High Very High
Eczema 2 95.60 Very High Very High Very High
Headache 3 95.56 Very High Very High Very High
Hirsutism 2 95.12 Very High Very High Very High
Gingival Hyperplasia 2 94.68 High High
Diplopia 2 92.36 High High
Ocular Toxicity (including Many Sub-types) 2 91.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As for abnormal laboratory test, transient increases in GOT, GPT, Al-P, LDH, serum Na, Cl and decrease in serum K were observed in 9 patients (11.4%).
Positive_regulation (increases) of Al-P
1) Confidence 0.09 Published 1996 Journal Jpn J Antibiot Section Abstract Doc Link 8851308 Disease Relevance 1.38 Pain Relevance 0.10
Biochemical examinations: indicated that the total bilirubin was decreased in 4.4%, serum AL-P was elevated in 26.2%, the total serum cholesterol increased above 200 mg/dl in 17.7% and decreased below 150 mg/dl in 8.9%, and serum P and K were reduced in 31.5% and 2.4%, respectively.
Positive_regulation (increased) of serum AL-P
2) Confidence 0.03 Published 1980 Journal Folia Psychiatr Neurol Jpn Section Abstract Doc Link 7216011 Disease Relevance 1.09 Pain Relevance 0.28
Biochemical examinations: indicated that the total bilirubin was decreased in 4.4%, serum AL-P was elevated in 26.2%, the total serum cholesterol increased above 200 mg/dl in 17.7% and decreased below 150 mg/dl in 8.9%, and serum P and K were reduced in 31.5% and 2.4%, respectively.
Positive_regulation (elevated) of serum AL-P
3) Confidence 0.03 Published 1980 Journal Folia Psychiatr Neurol Jpn Section Abstract Doc Link 7216011 Disease Relevance 1.08 Pain Relevance 0.28
In the patient who reported fever the drug was discontinued and in the patient who complained of pain at the site of injection, dosing was changed to the oral route but was discontinued due to elevated GOT, GPT, Al-P and gamma-GTP.
Positive_regulation (elevated) of Al-P associated with pain and fever
4) Confidence 0.02 Published 1989 Journal Jpn J Antibiot Section Abstract Doc Link 2540359 Disease Relevance 1.07 Pain Relevance 0.19
Slight elevation in S-GOT, S-GPT, Al-P and others was observed in 12 cases (8.8%) as abnormal laboratory test values.
Positive_regulation (elevation) of Al-P
5) Confidence 0.01 Published 1986 Journal Jpn J Antibiot Section Abstract Doc Link 3102807 Disease Relevance 0.51 Pain Relevance 0.15

General Comments

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