INT258783

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Latest revision as of 19:54, 22 September 2012

Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

vesicle-mediated transport (Ahi1) cytoskeleton (Ahi1) cilium (Ahi1)
cytoplasm (Ahi1)
Anatomy Link Frequency
T cell 2
Ahi1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 5 100.00 Very High Very High Very High
Inflammation 12 99.30 Very High Very High Very High
Endocannabinoid 16 98.40 Very High Very High Very High
Multiple sclerosis 52 93.64 High High
Central nervous system 9 93.32 High High
Cannabinoid 34 72.64 Quite High
Demyelination 3 61.36 Quite High
Pain 11 5.00 Very Low Very Low Very Low
cannabis 11 5.00 Very Low Very Low Very Low
Cannabinoid receptor 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 99.30 Very High Very High Very High
Multiple Sclerosis 64 93.64 High High
Disease Progression 1 91.44 High High
Injury 2 91.40 High High
Demyelinating Disease 4 61.36 Quite High
Autoimmune Disease 1 57.44 Quite High
Spasticity 51 50.00 Quite Low
Disease 12 44.84 Quite Low
Frailty 2 29.60 Quite Low
Cv Unclassified Under Development 1 22.08 Low Low

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, evidence suggests that endocannabinoids have immunosuppressant and anti-inflammatory properties, they downregulate the production of T helper 1 (Th1) cytokines, enhancing the production of T helper 2 (Th2) cytokines, since a polarization of T cell response towards a Th2 phenotype has been associated with therapeutic benefit in MS, while a shift towards Th1 has been associated with disease progression (Matsuda et al 1990; Hemmer 2002).
Positive_regulation (enhancing) of Gene_expression (production) of helper 1 in T cell associated with endocannabinoid, multiple sclerosis, inflammation, disease progression and cytokine
1) Confidence 0.04 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2626929 Disease Relevance 0.84 Pain Relevance 0.81

[edit] General Comments

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