INT258953

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.53
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Bcl6) nucleus (Bcl6) intracellular (Bcl6)
DNA binding (Bcl6)
Anatomy Link Frequency
epithelium 2
Bcl6 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 18 92.64 High High
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media With Effusion 82 99.84 Very High Very High Very High
Metaplasia 26 99.64 Very High Very High Very High
INFLAMMATION 20 92.64 High High
Infection 18 89.44 High High
Lymphatic System Cancer 4 74.72 Quite High
Otitis Media 12 50.00 Quite Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Mouth Breathing 4 5.00 Very Low Very Low Very Low
Bacterial Infection 4 5.00 Very Low Very Low Very Low
Snoring 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, we observed significant decreases in the respiratory epithelium of adenoid mucosa, significant increases of squamous epithelial metaplasia, and significant reductions of BCL-6 expression in OME patients.
Negative_regulation (reductions) of Gene_expression (expression) of BCL-6 in epithelium associated with metaplasia and otitis media with effusion
1) Confidence 0.19 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628093 Disease Relevance 0.80 Pain Relevance 0.07
Since we measured BCL-6 expression only after antigen stimulation, and since BCL-6 staining occurred primarily in the germinal centers, it may be that this transcription factor directly controls IgA production in the germinal centers.
Negative_regulation (measured) of Gene_expression (expression) of BCL-6
2) Confidence 0.14 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628093 Disease Relevance 0.73 Pain Relevance 0.07

General Comments

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