INT259135

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.21
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (KLK7) extracellular region (KLK7) cell adhesion (DSG2)
plasma membrane (DSG2)
Anatomy Link Frequency
BxPC-3 2
KLK7 (Homo sapiens)
DSG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 15 95.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Adenocarcinoma 14 100.00 Very High Very High Very High
Malignant Neoplastic Disease 6 95.96 Very High Very High Very High
Pancreatitis 17 95.24 Very High Very High Very High
Pancreatic Cancer 38 86.40 High High
Cancer 20 83.76 Quite High
Disease 2 59.96 Quite High
Adhesions 12 54.92 Quite High
Metastasis 3 5.00 Very Low Very Low Very Low
Stomach Cancer 2 5.00 Very Low Very Low Very Low
Skin Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, expression of KLK7 in the human pancreatic adenocarcinoma cell line BxPC-3 significantly increased the amount of soluble desmoglein 2 shed from the cell surface, which correlates with the in vitro degradation data.
Gene_expression (expression) of KLK7 in BxPC-3 Positive_regulation (increased) of desmoglein 2 associated with adenocarcinoma
1) Confidence 0.47 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2628383 Disease Relevance 1.21 Pain Relevance 0.16

General Comments

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