INT259925

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) peptidase activity (Plat) extracellular space (Plat)
extracellular region (Plat) nucleus (Jun) DNA binding (Jun)
Anatomy Link Frequency
macrophage 2
Plat (Mus musculus)
Jun (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 51.04 Quite High
metalloproteinase 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 8 54.32 Quite High
INFLAMMATION 14 51.04 Quite High
Disease 6 45.04 Quite Low
Breast Cancer 6 28.28 Quite Low
Cancer 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Resveratrol and 7 trans-stilbenes that contained one or more phenolic substituents were compared for their effects on the TPA-induced activation of AP-1 in an initial screening at 15 ?
Regulation (effects) of TPA Positive_regulation (activation) of AP-1
1) Confidence 0.05 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2632638 Disease Relevance 0 Pain Relevance 0
LMD directed the synthetic chemistry and helped design the study; LAH and AMG collected the data related to the effects of substituted trans-stilbenes on TPA-induced activation of AP-1; RAO designed and directed studies involving use of macrophage cells; and DLVJ helped design the study and wrote the manuscript.



Regulation (effects) of TPA Positive_regulation (activation) of AP-1 in macrophage
2) Confidence 0.05 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2632638 Disease Relevance 0.11 Pain Relevance 0.03

General Comments

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