INT260113

Context Info Confidence 0.32 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0.04

growth (FOXP3) nucleus (FOXP3) intracellular (FOXP3) embryo development (FOXP3) protein complex (FOXP3) cytoplasm (FOXP3)

Anatomy Link Frequency nTreg 2 FOXP3 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 21 79.32 cytokine 14 21.96 Arthritis 18 5.00 rheumatoid arthritis 9 5.00 tolerance 8 5.00 chemokine 5 5.00 methotrexate 3 5.00 corticosteroid 2 5.00 abatacept 1 5.00 Multiple sclerosis 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 21 79.32 Apoptosis 2 71.72 Rheumatic Diseases 12 50.00 Juvenile Chronic Polyarthritis 16 5.00 Disease 16 5.00 Autoimmune Disease 15 5.00 Systemic Lupus Erythematosus 13 5.00 Rheumatoid Arthritis 9 5.00 Sarcoidosis 4 5.00 Graft Vs Host Disease 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

However, the signals that induce the stable up-regulation of Foxp3 and committed regulatory function in nTreg are not known.

Positive_regulation (induce) of Regulation (regulation) of Foxp3 in nTreg

1) Confidence 0.32 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2633304 Disease Relevance 0.15 Pain Relevance 0.04

General Comments

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