INT261374

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Esr2) endoplasmic reticulum (Nsdhl) enzyme binding (Esr2)
DNA binding (Esr2) cytoplasm (Esr2) oxidoreductase activity (Nsdhl)
Nsdhl (Mus musculus)
Esr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Locus ceruleus 10 99.26 Very High Very High Very High
ketamine 3 45.92 Quite Low
Dopamine 35 5.00 Very Low Very Low Very Low
gABA 16 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 44 97.36 Very High Very High Very High
Apoptosis 12 90.16 High High
Schizophrenia 220 87.04 High High
Suicidal Behaviour 2 76.84 Quite High
Death 5 56.04 Quite High
Neurodegenerative Disease 6 47.68 Quite Low
Urological Neuroanatomy 4 7.28 Low Low
Disease 26 5.00 Very Low Very Low Very Low
Stress 14 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prenatal and neonatal exposure to BPA in rats causes increased LC volume in males and decreased volumes in females ultimately resulting in reversal of the sex differences normally observed in the rat LC.81 The reversal likely results from BPA's estrogenic effect on ERalpha and ERbeta that are expressed in the LC.


BPA Regulation (effect) of ERbeta associated with locus ceruleus
1) Confidence 0.05 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.76 Pain Relevance 0.41

General Comments

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