INT262377

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.47
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fmod) mitochondrion (Comt) extracellular region (Fmod)
methyltransferase activity (Comt) proteinaceous extracellular matrix (Fmod) intracellular (Fmod)
Comt (Mus musculus)
Fmod (Mus musculus)
Pain Link Frequency Relevance Heat
Fibrositis 77 100.00 Very High Very High Very High
Catechol-O-methyltransferase 1 100.00 Very High Very High Very High
Serotonin 6 99.48 Very High Very High Very High
Pain threshold 2 95.20 Very High Very High Very High
Neurotransmitter 6 88.80 High High
substance P 1 86.80 High High
imagery 1 84.04 Quite High
Pain 40 82.40 Quite High
Lasting pain 4 70.24 Quite High
Central nervous system 4 58.24 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 77 100.00 Very High Very High Very High
Pain 54 95.20 Very High Very High Very High
Chronic Fatigue Syndrome 2 73.44 Quite High
Rheumatic Diseases 1 48.92 Quite Low
INFLAMMATION 3 48.16 Quite Low
Thyroid Disease 1 46.96 Quite Low
Myofascial Pain Syndromes 1 46.32 Quite Low
Depressive Disorder 1 44.24 Quite Low
Anxiety Disorder 15 43.24 Quite Low
Restless Legs Syndrome 1 37.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specific polymorphisms in the serotonin transporter gene and the catechol-O-methyltransferase (enzyme inactivating catecholoamines) have been associated with FM occurrence (Cohen et al 2002;Gursay et al 2003).
catechol-O-methyltransferase Binding (associated) of FM associated with catechol-o-methyltransferase, fibrositis and serotonin
1) Confidence 0.06 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2646648 Disease Relevance 1.47 Pain Relevance 1.29

General Comments

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