INT262673

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tg) extracellular region (Tg) Golgi apparatus (Tg)
endoplasmic reticulum (Tg)
Tg (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 11 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Peripheral nervous system 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Nav1.1 3 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 153 28.28 Quite Low
Targeted Disruption 31 5.00 Very Low Very Low Very Low
Stress 26 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 22 5.00 Very Low Very Low Very Low
Syndrome 15 5.00 Very Low Very Low Very Low
Hypoxia 14 5.00 Very Low Very Low Very Low
Cognitive Disorder 13 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Apoptosis 11 5.00 Very Low Very Low Very Low
Amyloid Plaque 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As predicted, BACE1 is resistant to inhibition by pepstatin and has optimal activity at ~pH 4.5, being localized within acidic subcellular compartments of the secretory pathway, primarily the Golgi apparatus, TGN and endosomes.
Localization (localized) of TGN
1) Confidence 0.13 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 0 Pain Relevance 0

General Comments

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