INT262714

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.41
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (ACHE) lipid metabolic process (ACOT1) cytoplasm (ACOT1)
cell proliferation (ACHE) cytosol (ACOT1) extracellular space (ACHE)
Anatomy Link Frequency
brain 4
ACOT1 (Homo sapiens)
ACHE (Homo sapiens)
Pain Link Frequency Relevance Heat
Hippocampus 2 84.80 Quite High
Inflammation 2 34.08 Quite Low
Glutamate receptor 2 31.88 Quite Low
cINOD 8 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
fluoxetine 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 38 96.96 Very High Very High Very High
Disease 134 95.12 Very High Very High Very High
Dementia 20 85.96 High High
Alzheimer's Dementia 14 40.48 Quite Low
INFLAMMATION 6 34.08 Quite Low
Head Trauma 2 18.68 Low Low
Cerebrovascular Disease 2 17.00 Low Low
Depression 14 5.00 Very Low Very Low Very Low
Immunization 14 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The general mechanism of AChEI is to increase the brain availability of acetylcholine (ACh) through an inhibition of the enzyme acetylcholinesterase (AChE).
ACh Positive_regulation (increase) of Negative_regulation (inhibition) of AChE in brain
1) Confidence 0.06 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647161 Disease Relevance 0.70 Pain Relevance 0.04
The general mechanism of AChEI is to increase the brain availability of acetylcholine (ACh) through an inhibition of the enzyme acetylcholinesterase (AChE).
ACh Positive_regulation (increase) of Negative_regulation (inhibition) of acetylcholinesterase in brain
2) Confidence 0.06 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647161 Disease Relevance 0.70 Pain Relevance 0.04

General Comments

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