INT262875

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.58
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Paneth cells 1
DEFA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 2 59.08 Quite High
cytokine 10 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
spastic colon 4 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 16 100.00 Very High Very High Very High
Sprains And Strains 44 85.68 High High
Infection 31 61.64 Quite High
Disease 35 59.08 Quite High
Burns 29 56.16 Quite High
Bacterial Respiratory Disease 9 54.12 Quite High
Stress 6 45.88 Quite Low
Death 4 36.48 Quite Low
Multiple Organ Failure 3 36.08 Quite Low
Sepsis 2 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Certain epithelial defensins are constitutively expressed (HBD-1), whereas others are induced after tissue injury or exposure to microbes (HBD-2, HBD-3, and HNP-1).13 Paneth cells are a major source of ?
Positive_regulation (induced) of HNP-1 in Paneth cells associated with injury
1) Confidence 0.17 Published 2010 Journal Eplasty Section Body Doc Link PMC2803769 Disease Relevance 0.38 Pain Relevance 0
is the activation of the murine defensin cryptdin (an alpha-defensin that is
Positive_regulation (activation) of alpha-defensin
2) Confidence 0.01 Published 2008 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2648624 Disease Relevance 0.20 Pain Relevance 0.06

General Comments

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