INT263025

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (DEFA6) extracellular region (DEFA6)
DEFA6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 41 94.72 High High
Crohn's disease 21 88.00 High High
psoriasis 51 50.00 Quite Low
cytokine 22 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 37 94.72 High High
Skin Diseases 5 93.68 High High
Targeted Disruption 6 91.32 High High
Disease 66 88.00 High High
Inflammatory Bowel Disease 20 87.36 High High
Pouchitis 1 85.60 High High
Ileitis 1 81.60 Quite High
Psoriasis 70 50.00 Quite Low
Eczema 20 5.00 Very Low Very Low Very Low
Infection 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-defensin mRNA expression in biopsy specimens of ileal Crohn's patients, which was even more pronounced in patients carrying NOD2 mutations [58, 59], was observed.
Positive_regulation (pronounced) of Gene_expression (expression) of defensin mRNA
1) Confidence 0.16 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2992817 Disease Relevance 0.82 Pain Relevance 0.24
Genotyping of defensin copy number
Positive_regulation (Genotyping) of Gene_expression (Genotyping) of defensin
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2649503 Disease Relevance 0.19 Pain Relevance 0.05

General Comments

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