INT263686

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Neto1)
Anatomy Link Frequency
synapses 4
Neto1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pyramidal cell 8 96.52 Very High Very High Very High
Hippocampus 24 89.24 High High
antagonist 2 40.56 Quite Low
long-term potentiation 52 5.00 Very Low Very Low Very Low
nMDA receptor 18 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 12 14.92 Low Low
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Influenza Virus Infection 2 5.00 Very Low Very Low Very Low
Contagious Ecthyma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these findings indicate that lack of Neto1 does not alter the total surface expression of NMDARs, but rather decreases the targeting or stability of NR2A-containing NMDARs at synapses.
Negative_regulation (decreases) of Neto1 Neg (lack) Binding (lack) of in synapses
1) Confidence 0.43 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0 Pain Relevance 0.13
Collectively, these findings indicate that lack of Neto1 does not alter the total surface expression of NMDARs, but rather decreases the targeting or stability of NR2A-containing NMDARs at synapses.
Neg (not) Negative_regulation (alter) of Neto1 Neg (lack) Binding (lack) of in synapses
2) Confidence 0.43 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0 Pain Relevance 0.13

General Comments

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