INT263759

Context Info Confidence 0.29 First Reported 2009 Last Reported 2009 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.17 Pain Relevance 0.07

transport (Grin1, Grin2a) plasma membrane (Grin1, Grin2a) locomotion (Grin2a) enzyme binding (Grin1) cytoplasm (Grin1)

Anatomy Link Frequency brain 2 Grin1 (Mus musculus) Grin2a (Mus musculus)

Pain Link Frequency Relevance Heat Hippocampus 12 96.16 long-term potentiation 26 23.28 nMDA receptor 9 5.00 Pyramidal cell 4 5.00 Central nervous system 3 5.00 Neurotransmitter 3 5.00 Glutamate receptor 2 5.00 Eae 2 5.00 Glutamate 2 5.00 tetrodotoxin 1 5.00

Disease Link Frequency Relevance Heat Congenital Anomalies 6 89.12 Cognitive Disorder 8 5.00 Convulsion 2 5.00 Sprains And Strains 1 5.00 Helminth Infection 1 5.00 Influenza Virus Infection 1 5.00 Contagious Ecthyma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The absence of Neto1 had no effect on the overall abundance of NR1, NR2A, NR2B, PSD-95, GluR2, VAMP2, or GABAAR1 proteins (Figure 6L) in whole brain extracts, or of NR1, NR2A, NR2B, or PSD-95 in crude synaptosomes (Figure 6M).

NR1 Neg (no) Regulation (effect) of Localization (abundance) of NR2A in brain

1) Confidence 0.29 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0.17 Pain Relevance 0.07

General Comments

This test has worked.