INT263877

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 3
Speculated 0
Reported most in Body
Documents 1
Total Number 19
Disease Relevance 11.58
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
lymph node 1
abdomen 1
Rigs1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1653 54.88 Quite High
positron emission tomography 684 5.00 Very Low Very Low Very Low
Somatostatin 228 5.00 Very Low Very Low Very Low
anesthesia 76 5.00 Very Low Very Low Very Low
lidocaine 38 5.00 Very Low Very Low Very Low
cerebral cortex 19 5.00 Very Low Very Low Very Low
Inflammation 19 5.00 Very Low Very Low Very Low
local anesthetic 19 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 285 100.00 Very High Very High Very High
Colon Cancer 1197 99.96 Very High Very High Very High
Disease 1235 99.48 Very High Very High Very High
Cancer 4047 98.82 Very High Very High Very High
Adenocarcinoma 266 98.40 Very High Very High Very High
Merkel Cell Carcinoma 209 97.92 Very High Very High Very High
Skin Cancer 741 96.88 Very High Very High Very High
Reprotox - General 1 228 96.04 Very High Very High Very High
Carcinoma 190 94.60 High High
Metastasis 950 93.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RIGS with 125I-anti-CEA monoclonal antibody (125I-A5B7) and 99Tc-anti-CEA monoclonal antibody fragment (99Tc-IMMU-4)
Gene_expression (antibody) of RIGS
1) Confidence 0.08 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.78 Pain Relevance 0
Retroperitoneal disease was a common finding for RIGS nonresectability.
Gene_expression (nonresectability) of RIGS associated with disease
2) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.42 Pain Relevance 0
In the group of 16 asymptomatic patients with a history of previously treated colorectal cancer who has a rising CEA, they found recurrent disease in only nine of 16 patients (56.2%) by traditional surgical exploration alone, but in 14 of 16 patients (87.5%) using a combined approach of traditional surgical exploration and RIGS, thus demonstrating that RIGS detected over-looked recurrent disease in five of 16 patients (31.3%) [303].
Gene_expression (detected) of RIGS associated with colon cancer and disease
3) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.88 Pain Relevance 0
Four days later, the patient underwent RIGS with surgical excision of a RIGS-positive lymph node in the left supraclavicular region that confirmed the diagnosis of metastatic prostate cancer.
Gene_expression (excision) of RIGS in lymph node associated with reprotox - general 1
4) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.87 Pain Relevance 0
Significant differences in survival were observed in the RIGS resectable versus traditional nonresectable, p < 0.0001; RIGS resectable versus RIGS nonresectable, p < 0.0008; and non-significant differences were noted in the traditional nonresectable versus RIGS nonresectable groups (p = 0.24).
Gene_expression (nonresectable) of RIGS
5) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.40 Pain Relevance 0
All sites suspicious for tumor by traditional assessment of the abdomen were found to be RIGS positive.
Gene_expression (positive) of RIGS in abdomen associated with cancer
6) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.98 Pain Relevance 0
Likewise, they determined that the use of RIGS influenced the overall surgical procedure performed in 2 of 43 cases (4.6%) of primary colorectal cancer and in three of nine cases (33%) of recurrent colorectal cancer.
Gene_expression (use) of RIGS associated with colon cancer
7) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 1.01 Pain Relevance 0
By RIGS status, 24 and 35 were RIGS-negative and RIGS-positive, respectively.
Neg (negative) Gene_expression (negative) of RIGS
8) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.42 Pain Relevance 0
By RIGS status, 24 and 35 were RIGS-negative and RIGS-positive, respectively.
Neg (negative) Gene_expression (negative) of RIGS
9) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.42 Pain Relevance 0
Significant differences in survival were observed in the RIGS resectable versus traditional nonresectable, p < 0.0001; RIGS resectable versus RIGS nonresectable, p < 0.0008; and non-significant differences were noted in the traditional nonresectable versus RIGS nonresectable groups (p = 0.24).
Gene_expression (nonresectable) of RIGS
10) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.34 Pain Relevance 0
RIGS overview
Gene_expression (overview) of RIGS
11) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 1.27 Pain Relevance 0.03
Two-, three-, four-, and five-year survival data were reported for three classifications of patients: RIGS resectable (n = 40), traditional nonresectable (n = 33), and RIGS nonresectable (n = 13).
Gene_expression (resectable) of RIGS
12) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.34 Pain Relevance 0
Traditional surgical exploration and RIGS were performed.
Gene_expression (exploration) of RIGS
13) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.51 Pain Relevance 0
Significant differences in survival were observed in the RIGS resectable versus traditional nonresectable, p < 0.0001; RIGS resectable versus RIGS nonresectable, p < 0.0008; and non-significant differences were noted in the traditional nonresectable versus RIGS nonresectable groups (p = 0.24).
Gene_expression (nonresectable) of RIGS
14) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.40 Pain Relevance 0
At surgery, all RIGS-positive tissue was considered malignant and excised whenever possible.
Gene_expression (excised) of RIGS associated with malignant neoplastic disease
15) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.69 Pain Relevance 0
Table 5 provides the sensitivity of traditional exploration and RIGS exploration using 125I-HuCC49?
Gene_expression (exploration) of RIGS
16) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.43 Pain Relevance 0
Two-, three-, four-, and five-year survival data were reported for three classifications of patients: RIGS resectable (n = 40), traditional nonresectable (n = 33), and RIGS nonresectable (n = 13).
Gene_expression (nonresectable) of RIGS
17) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.33 Pain Relevance 0
Specimens were divided into tissue types I through IV, based on antibody localization and hematoxylin and eosin staining: type I, RIGS negative and histologically negative; type II, RIGS negative and histologically positive; type III, RIGS positive and histologically negative; and type IV, RIGS positive and histologically positive.
Neg (negative) Gene_expression (negative) of RIGS
18) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.75 Pain Relevance 0
Significant differences in survival were observed in the RIGS resectable versus traditional nonresectable, p < 0.0001; RIGS resectable versus RIGS nonresectable, p < 0.0008; and non-significant differences were noted in the traditional nonresectable versus RIGS nonresectable groups (p = 0.24).
Gene_expression (resectable) of RIGS
19) Confidence 0.07 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.35 Pain Relevance 0

General Comments

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