INT264527

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.75 Pain Relevance 0.38

extracellular space (IL1B, PTGDS) extracellular region (IL1B, PTGDS) isomerase activity (PTGDS) transport (PTGDS) aging (IL1B) Golgi apparatus (PTGDS)

Anatomy Link Frequency chondrocytes 2 IL1B (Homo sapiens) PTGDS (Homo sapiens)

Pain Link Frequency Relevance Heat Osteoarthritis 47 99.56 Inflammation 22 5.00 cytokine 5 5.00 metalloproteinase 4 5.00 COX-2 inhibitor 1 5.00 Central nervous system 1 5.00 cINOD 1 5.00 Inflammatory response 1 5.00 Pain 1 5.00 Multiple sclerosis 1 5.00

Disease Link Frequency Relevance Heat Osteoarthritis 48 99.56 INFLAMMATION 24 5.00 Disease 8 5.00 Targeted Disruption 4 5.00 Atherosclerosis 3 5.00 Apoptosis 3 5.00 Crystal Associated Disease 2 5.00 Hypertension 1 5.00 Demyelinating Disease 1 5.00 Arthritis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interleukin-1-beta induces L-PGDS expression in chondrocytes

Interleukin-1-beta Positive_regulation (induces) of Gene_expression (expression) of L-PGDS in chondrocytes

1) Confidence 0.07 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656251 Disease Relevance 0.75 Pain Relevance 0.38

General Comments

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