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|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| First Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Last Reported
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
|-
 
|-
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"| Negated
Line 48: Line 48:
 
fontcolor=white,
 
fontcolor=white,
 
label="Binding",
 
label="Binding",
URL=Binding
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=E:Binding"
 
];
 
];
 
node2
 
node2
Line 56: Line 56:
 
fontcolor=white,
 
fontcolor=white,
 
label="CYP2C19",
 
label="CYP2C19",
URL="CYP2C19"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:1557"
 
];
 
];
 
node3
 
node3
Line 64: Line 64:
 
fontcolor=white,
 
fontcolor=white,
 
label="CYP3A4",
 
label="CYP3A4",
URL="CYP3A4"
+
URL="http://wikipaints.org/vhosts/wikipaints/mediawiki-1.19.1/index.php?title=G:1576"
 
];
 
];
 
subgraph cluster_0 {
 
subgraph cluster_0 {
Line 78: Line 78:
 
{| cellspacing=5 cellpadding=2
 
{| cellspacing=5 cellpadding=2
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[small molecule metabolic process]] ([[CYP2C19]], [[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:small molecule metabolic process|small molecule metabolic process]] ([[G:1557|CYP2C19]], [[G:1576|CYP3A4]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[oxidoreductase activity]] ([[CYP2C19]], [[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:oxidoreductase activity|oxidoreductase activity]] ([[G:1557|CYP2C19]], [[G:1576|CYP3A4]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[endoplasmic reticulum]] ([[CYP2C19]], [[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:endoplasmic reticulum|endoplasmic reticulum]] ([[G:1557|CYP2C19]], [[G:1576|CYP3A4]])
 
|-
 
|-
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[enzyme binding]] ([[CYP2C19]], [[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:enzyme binding|enzyme binding]] ([[G:1557|CYP2C19]], [[G:1576|CYP3A4]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[lipid metabolic process]] ([[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:lipid metabolic process|lipid metabolic process]] ([[G:1576|CYP3A4]])
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[cytoplasm]] ([[CYP3A4]])
+
| style="color: black; background:#F7F7CD; border: 1px solid lightgray; white-space:wrap;"| [[GOS:cytoplasm|cytoplasm]] ([[G:1576|CYP3A4]])
 
|-
 
|-
 
|}
 
|}
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Pain Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[methadone]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:methadone|methadone]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 27
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 27
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 99.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}} {{#icon: chilli.png|Very High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[action potential duration]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:action potential duration|action potential duration]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 72.08
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Action potential]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Action potential|Action potential]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 68.64
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[drug abuse]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:drug abuse|drug abuse]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[cocaine]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:cocaine|cocaine]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 49.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 49.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[potassium channel]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:potassium channel|potassium channel]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 40.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 40.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[withdrawal]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:addiction|addiction]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Angina]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:withdrawal|withdrawal]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[alcohol]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:Angina|Angina]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[addiction]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[P:alcohol|alcohol]]
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 5.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}} {{#icon: cold.png|Very Low}}
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{| cellspacing=1 cellpadding=5 align=center
 
{| cellspacing=1 cellpadding=5 align=center
 
|-
 
|-
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Term
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Disease Link
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Frequency
! style="color: black; background:#AAFCFB; white-space:wrap;"| Confidence
+
! style="color: black; background:#AAFCFB; white-space:wrap;"| Relevance
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
! style="color: black; background:#AAFCFB; white-space:wrap;"| Heat
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Arrhythmia Under Development]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Arrhythmia Under Development|Arrhythmia Under Development]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 93.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Cv Unclassified Under Development]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Cv Unclassified Under Development|Cv Unclassified Under Development]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 2
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 91.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Hypokalemia]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Hypokalemia|Hypokalemia]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 85.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 85.12
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|High}} {{#icon: chilli.png|High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Heart Rate Under Development]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Heart Rate Under Development|Heart Rate Under Development]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 75.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Syndrome]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Syndrome|Syndrome]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 8
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 56.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Congenital Anomalies]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Congenital Anomalies|Congenital Anomalies]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.72
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: chilli.png|Quite High}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Drug Dependence]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Drug Dependence|Drug Dependence]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 4
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 50.00
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Coronary Heart Disease]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Coronary Heart Disease|Coronary Heart Disease]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 1
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 36.52
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Infection]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Infection|Infection]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 7
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32.96
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| {{#icon: cold.png|Quite Low}}
 
|-
 
|-
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[Acquired Immune Deficiency Syndrome Or Hiv Infection]]
+
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| [[D:Acquired Immune Deficiency Syndrome Or Hiv Infection|Acquired Immune Deficiency Syndrome Or Hiv Infection]]
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 14
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32.56
 
| style="background:#E0FFFF; border: 1px solid white; white-space:wrap;"| 32.56
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{| cellpadding=4 cellspacing=2  
 
{| cellpadding=4 cellspacing=2  
 
|-
 
|-
| <span style="color:#800000">'''CYP2C19'''</span> <span style="color:#000080">'''Binding'''</span> (<span style="color:#000080">metabolize</span>) of <span style="color:#800000">'''CYP3A4'''</span> associated with <span style="color:#FF0000">'''methadone'''</span>
+
|  [[G:1557|<span style="color:#800000">'''CYP2C19'''</span>]] [[E:Binding|<span style="color:#000080">'''Binding'''</span>]] (<span style="color:#000080">metabolize</span>) of [[G:1576|<span style="color:#800000">'''CYP3A4'''</span>]] associated with <span style="color:#FF0000">'''methadone'''</span>
 
|-
 
|-
 
|}
 
|}
Line 256: Line 256:
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 0.18
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Published
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| 2008
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[Y:2008|2008]]
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
! style="color: black; background:#AAFCFB; border: 1px solid lightgray; white-space:nowrap;"|    Journal
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Int J Emerg Med|Int J Emerg Med]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;"  align="center"| [[J:Int J Emerg Med|Int J Emerg Med]]

Latest revision as of 08:38, 20 September 2012

Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP2C19, CYP3A4) oxidoreductase activity (CYP2C19, CYP3A4) endoplasmic reticulum (CYP2C19, CYP3A4)
enzyme binding (CYP2C19, CYP3A4) lipid metabolic process (CYP3A4) cytoplasm (CYP3A4)
CYP2C19 (Homo sapiens)
CYP3A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
methadone 27 99.96 Very High Very High Very High
action potential duration 1 72.08 Quite High
Action potential 2 68.64 Quite High
drug abuse 5 50.00 Quite Low
cocaine 8 49.12 Quite Low
potassium channel 2 40.00 Quite Low
addiction 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arrhythmia Under Development 32 93.72 High High
Cv Unclassified Under Development 2 91.12 High High
Hypokalemia 1 85.12 High High
Heart Rate Under Development 14 75.72 Quite High
Syndrome 8 56.00 Quite High
Congenital Anomalies 4 50.72 Quite High
Drug Dependence 4 50.00 Quite Low
Coronary Heart Disease 1 36.52 Quite Low
Infection 7 32.96 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 14 32.56 Quite Low

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It specifically inhibits the CYP2C19, CYP2C9, and CYP3A4 enzymes that metabolize methadone.
CYP2C19 Binding (metabolize) of CYP3A4 associated with methadone
1) Confidence 0.18 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2657284 Disease Relevance 0.72 Pain Relevance 1.09

[edit] General Comments

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