INT265759

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (KL, VEGFA) extracellular region (KL, VEGFA) aging (KL)
carbohydrate metabolic process (KL) cytoplasm (VEGFA) signal transducer activity (KL)
Anatomy Link Frequency
blood 2
KL (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 2 91.72 High High
Peripheral Arterial Disease 18 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Coronary Artery Disease 6 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Atherosclerosis 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Eclampsia 3 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Distribution changes were again more evident in the blood: the simultaneous elevations in free VEGF and sVEGFR1, due to increasing global kL (e.g., 10× from control), in turn synergistically increased sVEGFR1-VEGF complex formation (e.g., 88× from control), which elevated the complexed fractions of both VEGF (e.g., +13%) and sVEGFR1 (e.g., +8.7%).
kL Positive_regulation (increasing) of sVEGFR1-VEGF Binding (formation) of in blood
1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.14 Pain Relevance 0

General Comments

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