INT266835

Context Info Confidence 0.19 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

transport (Slc34a3) extracellular space (Pth)

Anatomy Link Frequency tubule 1 Pth (Mus musculus) Slc34a3 (Mus musculus)

Pain Link Frequency Relevance Heat Somatostatin 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Familial Hypophosphatemia 3 72.64 Rickets 73 50.00 Hypophosphatemia 11 45.04 Cancer 12 5.00 Disease 10 5.00 Kidney Stones 5 5.00 Syndrome 4 5.00 Hypercalcemia 3 5.00 Congenital Anomalies 3 5.00 Phosphate Metabolism Disorders 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NaPi-IIa and NaPi-IIc are the major transporters in the proximal tubule and are regulated by PTH, which internalises the transporters and increases their catabolism, thus, reducing Pi reabsorption.

PTH Regulation (regulated) of NaPi-IIc in tubule

1) Confidence 0.19 Published 2008 Journal Eur J Pediatr Section Body Doc Link PMC2668657 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.