INT267015

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) extracellular region (Bdnf)
cytoplasmic membrane-bounded vesicle (Bdnf) plasma membrane (Ephb1) cytoplasm (Ephb1)
Anatomy Link Frequency
striatum 1
Ephb1 (Rattus norvegicus)
Bdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 7 5.00 Very Low Very Low Very Low
GABAergic 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 6 67.04 Quite High
Disease 7 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Brain Disease 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas the above studies were performed in cells cultured from embryonic rat brain, we wished to explore whether ERK also played a major role in the BDNF-mediated regulation of gene expression in the mature striatum.
ERK Spec (whether) Regulation (regulation) of BDNF-mediated in striatum
1) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2669182 Disease Relevance 0.07 Pain Relevance 0

General Comments

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