INT267401

Context Info Confidence 0.01 First Reported 2009 Last Reported 2009 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cell adhesion (ITGA4) plasma membrane (ITGA4)

ITGA4 (Homo sapiens)

Pain Link Frequency Relevance Heat Eae 3 5.00 Neuritis 1 5.00

Disease Link Frequency Relevance Heat Repression 15 5.00 Targeted Disruption 11 5.00 Sprains And Strains 7 5.00 Neuritis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These events most likely involve the reciprocal regulation of the phosphorylation status of PER by DBT and CKII, whereby CKII function seems crucially important for efficient nuclear localization of PER in wild-type flies [20,32,33,41].

Spec (seems) Positive_regulation (important) of Localization (localization) of wild-type

1) Confidence 0.01 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2671555 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.