INT267592

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL6, MUC1) extracellular space (IL6) aging (IL6)
plasma membrane (MUC1) nucleus (MUC1) cytoplasm (MUC1)
Anatomy Link Frequency
epithelial cells 2
IL6 (Homo sapiens)
MUC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 63 88.36 High High
Inflammation 111 52.08 Quite High
Inflammatory mediators 24 5.00 Very Low Very Low Very Low
chemokine 17 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Deafness 4 98.28 Very High Very High Very High
Otitis Media With Effusion 92 96.40 Very High Very High Very High
Otitis Media 134 93.52 High High
Bacterial Infection 4 81.04 Quite High
Acute-phase Reaction 2 76.08 Quite High
Hematological Disease 1 73.16 Quite High
Infection 14 69.24 Quite High
Apoptosis 1 53.64 Quite High
INFLAMMATION 144 52.08 Quite High
Hypersensitivity 9 51.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In cultured middle ear epithelial cells, mucin secretion is upregulated by IL-6 in a dose and time-dependent manner.
IL-6 Positive_regulation (upregulated) of Localization (secretion) of mucin in epithelial cells
1) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.24 Pain Relevance 0.07

General Comments

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