INT268585

Context Info Confidence 0.24 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.01 Pain Relevance 0

cytosol (GLI1) nucleus (GLI1) intracellular (GLI1) DNA binding (GLI1) cytoplasm (GLI1)

GLI1 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 1 5.00 addiction 1 5.00

Disease Link Frequency Relevance Heat Cancer 124 95.48 Glioma 1 84.28 Liver Cancer 1 68.72 Lung Cancer 5 52.72 Apoptosis 22 5.00 Chronic Lymphoid Leukemia 7 5.00 Prostate Cancer 6 5.00 Lymphatic System Cancer 5 5.00 Adenocarcinoma 5 5.00 Death 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

They found that their designed synthetic miRNAs reduced expression of the Gli-1 protein and inhibited cell proliferation and division.

Negative_regulation (reduced) of Gene_expression (expression) of Gli-1

1) Confidence 0.24 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674802 Disease Relevance 1.01 Pain Relevance 0

General Comments

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