INT271212

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SEMA6A) plasma membrane (SEMA6A) cytoskeleton organization (SEMA6A)
Anatomy Link Frequency
neurons 2
SEMA6A (Homo sapiens)
Pain Link Frequency Relevance Heat
Neurotransmitter 7 97.28 Very High Very High Very High
Serotonin 13 95.60 Very High Very High Very High
cytokine 63 80.08 Quite High
depression 23 50.00 Quite Low
Glutamate 3 18.72 Low Low
monoamine 3 5.16 Low Low
Inflammation 40 5.00 Very Low Very Low Very Low
antidepressant 10 5.00 Very Low Very Low Very Low
Multiple sclerosis 6 5.00 Very Low Very Low Very Low
Etanercept 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 17 95.52 Very High Very High Very High
Disease 13 79.44 Quite High
Schizophrenia 5 56.48 Quite High
Depression 29 50.00 Quite Low
Autoimmune Disease 3 36.60 Quite Low
Sleep Paralysis 1 25.20 Quite Low
Hallucination 1 24.36 Low Low
INFLAMMATION 41 5.00 Very Low Very Low Very Low
Obesity 19 5.00 Very Low Very Low Very Low
Weight Gain 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
may lead to psychiatric disorders via an activation of a neuroendocrine system such as the HPA axis, the activation of neurotransmitter transporters such as the serotonin transporter, the influence on the metabolism of neurotransmitters and the autoimmune destruction of neurons.


Spec (may) Positive_regulation (lead) of Positive_regulation (activation) of via in neurons associated with neurotransmitter and serotonin
1) Confidence 0.06 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687935 Disease Relevance 0.49 Pain Relevance 0.18

General Comments

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