INT271365

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.98
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PIGF)
Anatomy Link Frequency
thyroid 1
platelet 1
lung 1
PIGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 136 95.64 Very High Very High Very High
Inflammation 76 87.04 High High
ischemia 96 68.96 Quite High
Inflammatory marker 4 40.68 Quite Low
metalloproteinase 20 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 84 99.32 Very High Very High Very High
Necrosis 92 98.80 Very High Very High Very High
Urological Neuroanatomy 112 97.92 Very High Very High Very High
Angina 136 95.64 Very High Very High Very High
Acute Coronary Syndrome 280 95.08 Very High Very High Very High
Atherosclerosis 20 90.20 High High
INFLAMMATION 84 87.04 High High
Rupture 32 81.96 Quite High
Natriuresis 44 79.36 Quite High
Cancer 8 75.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Originally identified in the placenta (Maglione D et al. 1991), PIGF mRNA is expressed by various tissues, including thyroid and lung (Tjwa M et al. 2003).
Gene_expression (expressed) of PIGF mRNA in thyroid
1) Confidence 0.21 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.87 Pain Relevance 0.04
The predictive value of PIGF levels is independent of myocardial necrosis, as evidenced by elevated troponin levels (Heeschen C et al. 1999), as well as platelet activation, as evidenced by elevation of sCD40L (Heeschen C et al. 2003a).
Gene_expression (levels) of PIGF in platelet associated with necrosis
2) Confidence 0.19 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 1.07 Pain Relevance 0.23
In this study MPO, sCD40L and MMP-9 levels were not independently associated with death, whereas patients with increased levels of PIGF, NT-proBNP, CRP, cTnI or decreased eGFR had higher mortality rate than patients with normal value of these biomarkers.
Gene_expression (levels) of PIGF associated with urological neuroanatomy and death
3) Confidence 0.19 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 1.16 Pain Relevance 0
Originally identified in the placenta (Maglione D et al. 1991), PIGF mRNA is expressed by various tissues, including thyroid and lung (Tjwa M et al. 2003).
Gene_expression (expressed) of PIGF mRNA in lung
4) Confidence 0.07 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.87 Pain Relevance 0.04

General Comments

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