INT271499

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Context Info
Confidence 0.66
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnfsf15) plasma membrane (Tnfsf15)
Anatomy Link Frequency
lymphocytes 1
Tnfsf15 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 98.16 Very High Very High Very High
Crohn's disease 24 95.08 Very High Very High Very High
member 8 2 64.72 Quite High
Arthritis 14 5.00 Very Low Very Low Very Low
spinal inflammation 14 5.00 Very Low Very Low Very Low
psoriasis 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 98.16 Very High Very High Very High
Disease 36 95.08 Very High Very High Very High
Necrosis 2 63.32 Quite High
Cancer 2 62.96 Quite High
Spondylarthropathies 4 12.08 Low Low
Inflammatory Bowel Disease 14 5.00 Very Low Very Low Very Low
Low Back Pain 14 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 8 5.00 Very Low Very Low Very Low
Uveitis 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A full re-sequencing of all exons, 1st and 3rd introns, and additional intronic boundaries of the TNFSF15 gene in several patients and controls did not reveal unmatched variations either (data not shown).
Gene_expression (boundaries) of TNFSF15
1) Confidence 0.66 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2689651 Disease Relevance 0.25 Pain Relevance 0.09
Its product, TNFSF15, also called TLA1, is implicated in the modulation of T-helper 17 lymphocytes activation [32], the number of which has been shown to be increased in patients with SpA [34].
Gene_expression (product) of TNFSF15 in lymphocytes
2) Confidence 0.59 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2689651 Disease Relevance 0.38 Pain Relevance 0.15

General Comments

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