INT271874

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10, TNF) extracellular region (IL10, TNF) intracellular (IL10, TNF)
signal transduction (TNF) plasma membrane (TNF) extracellular matrix organization (TNF)
IL10 (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 99.36 Very High Very High Very High
cytokine 28 97.68 Very High Very High Very High
rheumatoid arthritis 63 95.28 Very High Very High Very High
Arthritis 5 90.60 High High
Inflammation 15 74.08 Quite High
methotrexate 39 5.00 Very Low Very Low Very Low
Etanercept 18 5.00 Very Low Very Low Very Low
Infliximab 18 5.00 Very Low Very Low Very Low
Adalimumab 8 5.00 Very Low Very Low Very Low
anakinra 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 18 99.00 Very High Very High Very High
Rheumatoid Arthritis 64 95.28 Very High Very High Very High
Juvenile Chronic Polyarthritis 1 90.60 High High
Disease 17 63.04 Quite High
Hematological Disease 1 56.36 Quite High
Adverse Drug Reaction 1 9.28 Low Low
Toxicity 10 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 5 5.00 Very Low Very Low Very Low
Opportunistic Infections 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specifically, IL-10 acts as a negative autocrine regulator of TNF-?
IL-10 Negative_regulation (regulator) of TNF
1) Confidence 0.07 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691664 Disease Relevance 0.78 Pain Relevance 0.50

General Comments

This test has worked.

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