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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tsc1) embryo development (Tsc1) protein complex (Tsc1)
cytoplasm (Tsc1)
Tsc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 1 14.16 Low Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hamartoma 8 98.58 Very High Very High Very High
Cancer 20 97.16 Very High Very High Very High
Disease 21 82.40 Quite High
Anaplastic Astrocytoma 6 75.76 Quite High
Tuberous Sclerosis 11 50.00 Quite Low
Myeloid Leukemia 5 33.36 Quite Low
Lymphangioleiomyomatosis 11 31.40 Quite Low
Angiomyolipoma 12 27.80 Quite Low
Lung Cancer 1 25.84 Quite Low
Hyperplasia 1 24.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For many years, the prevailing model has been that the hamartomas of TSC develop through a two-hit mechanism in which there is complete loss of expression of functional TSC1 or TSC2, supported by findings of loss of heterozygosity (LOH) in TSC tumour samples [23-26].
Negative_regulation (loss) of Gene_expression (expression) of TSC1 associated with cancer and hamartoma
1) Confidence 0.38 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.44 Pain Relevance 0

General Comments

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