INT271998

Context Info Confidence 0.17 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0

cytoplasm (Cdk1, Tsc1) mitochondrion (Cdk1) embryo development (Tsc1) protein complex assembly (Cdk1) protein complex (Tsc1) cytosol (Tsc1)

Cdk1 (Mus musculus) Tsc1 (Mus musculus)

Pain Link Frequency Relevance Heat cerebral cortex 1 5.00 transdermal 1 5.00 adenocard 1 5.00 Angina 1 5.00

Disease Link Frequency Relevance Heat Disease 21 89.20 Cancer 20 71.08 Papillomavirus Infection 1 60.12 Tuberous Sclerosis 11 50.00 Syndrome 2 34.20 Polycystic Kidney Disease 6 27.60 Angiomyolipoma 12 5.00 Lymphangioleiomyomatosis 11 5.00 Convulsion 9 5.00 Hamartoma 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Cdk1 phosphorylates hamartin at several sites, of which the phosphorylation at T310 regulates its interaction with Plk1 [43].

Cdk1 Positive_regulation (phosphorylates) of Phosphorylation (phosphorylates) of hamartin

1) Confidence 0.17 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.30 Pain Relevance 0

General Comments

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