INT273219

Context Info Confidence 0.22 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.10 Pain Relevance 0.20

lyase activity (Car1) Golgi apparatus (Car1) cytoplasm (Car1)

Car1 (Mus musculus)

Pain Link Frequency Relevance Heat depression 8 74.52 antagonist 5 65.20 Neuronal excitability 17 5.00 Hippocampus 6 5.00 hyperexcitability 3 5.00 anticonvulsant 3 5.00 medulla 2 5.00 tetrodotoxin 1 5.00 Central nervous system 1 5.00 ketamine 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 77 99.36 Anaerobic Bacterial Infections 8 82.80 Depression 8 74.52 Convulsion 68 16.64 Epilepsy 16 5.00 Shock 10 5.00 Status Epilepticus 7 5.00 Death 4 5.00 Malformations Of Cortical Development 2 5.00 Anxiety Disorder 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Responses to CA1 hippocampal tetanic stimuli in WT and Cdk5 KO mice

Regulation (Responses) of Positive_regulation (stimuli) of CA1 associated with targeted disruption

1) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 1.10 Pain Relevance 0.20

General Comments

This test has worked.