INT274215

Context Info Confidence 0.14 First Reported 2008 Last Reported 2008 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0

cytosol (Gsr) mitochondrion (Gsr) signal transduction (Mc3r) oxidoreductase activity (Gsr) plasma membrane (Mc3r) cytoplasm (Gsr)

Anatomy Link Frequency granulocytes 2 Mc3r (Mus musculus) Gsr (Mus musculus)

Pain Link Frequency Relevance Heat ischemia 6 50.00 chemokine 11 48.92 Inflammation 49 8.24 agonist 14 5.00 cytokine 6 5.00 Inflammatory response 6 5.00 adenocard 2 5.00 anesthesia 1 5.00 alcohol 1 5.00 Inflammatory stimuli 1 5.00

Disease Link Frequency Relevance Heat Injury 7 100.00 Adhesions 15 92.72 Cv Unclassified Under Development 6 50.00 INFLAMMATION 53 8.24 Urological Neuroanatomy 4 5.00 Vasculitis 3 5.00 Sprains And Strains 2 5.00 Arthritis 1 5.00 Necrosis 1 5.00 Peripheral Arterial Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Within the GR-1hi population, CD11b expression was not modified by the IR injury in either WT or MC3R-null animals; however, granulocytes from IR MC3R-null animals displayed an increased CD11b expression when compared with WT animals.

MC3R-null Neg (not) Positive_regulation (modified) of Gene_expression (expression) of GR-1hi in granulocytes associated with injury

1) Confidence 0.14 Published 2008 Journal FASEB J Section Body Doc Link PMC2700033 Disease Relevance 0.27 Pain Relevance 0

General Comments

This test has worked.