INT275479

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP2) extracellular space (MMP2) extracellular region (MMP2)
proteinaceous extracellular matrix (MMP2) plasma membrane (MMP2) nucleus (MMP2)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 118 88.88 High High
Inflammation 8 39.12 Quite Low
Hippocampus 2 27.84 Quite Low
Arthritis 5 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pathologic Processes 4 85.76 High High
Metastasis 9 83.52 Quite High
Wrinkles 5 82.32 Quite High
Fibrosarcoma 7 70.72 Quite High
Wound Healing 2 59.36 Quite High
INFLAMMATION 13 53.28 Quite High
Injury 1 37.36 Quite Low
Osteoporosis 2 31.68 Quite Low
Cancer 23 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This inhibition was caused by the decrease in gene expression and transcriptional activity of MMP-2[25].
Negative_regulation (decrease) of Transcription (activity) of MMP-2
1) Confidence 0.25 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2707034 Disease Relevance 0 Pain Relevance 0.04
kDa has been reported to have a strong inhibitory effect on MMP-2 by decreasing the gene expression and transcriptional activity of MMP-2.
Negative_regulation (decreasing) of Transcription (activity) of MMP-2
2) Confidence 0.12 Published 2010 Journal Biochemistry Research International Section Body Doc Link PMC3004377 Disease Relevance 0.43 Pain Relevance 0.11

General Comments

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