INT276062

Context Info Confidence 0.01 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

nucleus (Rtcd1, Prkaca) mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca) cytoplasm (Prkaca) ligase activity (Rtcd1)

Rtcd1 (Mus musculus) Prkaca (Mus musculus)

Pain Link Frequency Relevance Heat Dopamine 1 8.24 gABA 11 5.00 depression 9 5.00 imagery 5 5.00 long-term potentiation 4 5.00 Central nervous system 2 5.00 interneuron 1 5.00 Kinase C 1 5.00 Serotonin 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Depression 9 5.00 Adhesions 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It was suggested that GABABR suppresses the RP induction by reducing the amount of cAMP and the PKA activity by Gi-mediated inhibition of adenylyl cyclase (Kawaguchi and Hirano, 2000).

Negative_regulation (inhibition) of cyclase Negative_regulation (reducing) of PKA

1) Confidence 0.01 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2710870 Disease Relevance 0 Pain Relevance 0

General Comments

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