INT276180

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Pten) aging (Pten) plasma membrane (Pten)
nucleus (Pten) intracellular (Pten) enzyme binding (Pten)
Anatomy Link Frequency
muscle 2
Pten (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 60 93.40 High High
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperglycemia 4 99.32 Very High Very High Very High
Aging 38 98.82 Very High Very High Very High
Apoptosis 10 68.96 Quite High
Frailty 5 67.84 Quite High
Obesity 2 48.32 Quite Low
Muscle Disease 1 13.04 Low Low
Body Weight 4 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, aging-associated hyperglycemia and decreases in pPTEN level may result in decreased PTEN protein levels, which could act to increase the phosphorylation of Akt at Thr308 in aging muscle.
Spec (may) Positive_regulation (result) of Negative_regulation (decreased) of PTEN protein in muscle associated with hyperglycemia and aging
1) Confidence 0.35 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2712760 Disease Relevance 0.89 Pain Relevance 0.43

General Comments

This test has worked.

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