INT276337

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Timp1, Il10) extracellular space (Il10) proteinaceous extracellular matrix (Timp1)
intracellular (Il10)
Anatomy Link Frequency
B cell 1
Timp1 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 94.24 High High
chemokine 5 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
B-cell Lymphoma 27 99.60 Very High Very High Very High
Colon Cancer 1 92.68 High High
Diffuse Large B-cell Lymphoma 56 83.80 Quite High
Lymphatic System Cancer 122 80.44 Quite High
Epstein-barr Virus 30 79.04 Quite High
Hodgkin's Disease 25 45.68 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 15 21.68 Low Low
Aggression 1 13.28 Low Low
Cancer 41 8.32 Low Low
Mantle-cell Lymphoma 33 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TIMP1 downregulates B cell receptor and BCL6 and activates interleukin (IL)-6, IL-10/signal transducer, and activator of transcription-3 (STAT3) signaling in GC B cells.
TIMP1 Positive_regulation (activates) of IL-10 in B cell
1) Confidence 0.01 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 0.76 Pain Relevance 0.05

General Comments

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