INT277012

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PAPPA, ACE2) extracellular region (PAPPA, ACE2) cell differentiation (PAPPA)
extracellular space (ACE2) plasma membrane (ACE2)
Anatomy Link Frequency
smooth muscle cells 1
PAPPA (Homo sapiens)
ACE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 5 65.36 Quite High
Angina 10 58.32 Quite High
Inflammation 11 55.40 Quite High
Bioavailability 1 53.28 Quite High
metalloproteinase 6 46.36 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chromosome Aberrations 1 99.92 Very High Very High Very High
Atherosclerosis 14 84.40 Quite High
Urological Neuroanatomy 10 82.56 Quite High
Cardiovascular Disease 2 77.76 Quite High
Injury 3 74.96 Quite High
Reperfusion Injury 1 66.12 Quite High
Cv Unclassified Under Development 5 65.36 Quite High
Acute Coronary Syndrome 35 63.80 Quite High
Myocardial Infarction 15 59.60 Quite High
Cv General 3 Under Development 9 58.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PAPP-A is a zinc-binding metalloprotease that indirectly activates insuline-like growth factor (IGF), a potent mitogen and chemotactic agent for vascular smooth muscle cells.
PAPP-A Binding (binding) of metalloprotease in smooth muscle cells
1) Confidence 0.02 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2716777 Disease Relevance 1.26 Pain Relevance 0.15

General Comments

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