INT277313

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Context Info
Confidence 0.52
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mbnl1, Slc6a11) transport (Slc6a11) mRNA processing (Mbnl1)
RNA binding (Mbnl1) nucleus (Mbnl1)
Anatomy Link Frequency
SK-N-SH 3
Mbnl1 (Mus musculus)
Slc6a11 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 10 92.24 High High
imagery 10 5.00 Very Low Very Low Very Low
gABA 9 5.00 Very Low Very Low Very Low
interneuron 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 21 75.16 Quite High
Spinocerebellar Ataxia Type 2 5 50.00 Quite Low
Disease 11 28.64 Quite Low
Targeted Disruption 20 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Huntington's Chorea 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hypopituitarism 2 5.00 Very Low Very Low Very Low
Movement Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show that overexpression of CUGBP1 in human SK-N-SH cells, or depletion of MBNL1, result in an upregulation of GABT4 that mimics the in vivo changes in steady state levels caused by CUGexp transcripts.
Negative_regulation (depletion) of MBNL1 in SK-N-SH Positive_regulation (result) of Positive_regulation (upregulation) of GABT4 in SK-N-SH
1) Confidence 0.52 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2719092 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

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