INT277710

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA1) small molecule metabolic process (ABCA1) Golgi apparatus (ABCA1)
ATPase activity (ABCA1) plasma membrane (ABCA1) intracellular (ABCA1)
Anatomy Link Frequency
stem cells 4
ABCA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 126 84.80 Quite High
Arthritis 4 57.28 Quite High
methotrexate 30 19.68 Low Low
corticosteroid 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
abatacept 2 5.00 Very Low Very Low Very Low
anti-cytokine treatment 2 5.00 Very Low Very Low Very Low
Etanercept 2 5.00 Very Low Very Low Very Low
Adalimumab 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immune System Diseases 4 89.84 High High
Rheumatoid Arthritis 128 84.80 Quite High
Disease 20 71.48 Quite High
Hodgkin's Disease 2 64.96 Quite High
Seronegative Spondarthritis 2 58.24 Quite High
Infection 18 5.00 Very Low Very Low Very Low
Rheumatic Diseases 8 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is generally accepted that the CD20 protein functions as a channel regulator of ion influx (Ernst et al 2005) and that this membrane-bound protein is specifically found on the membrane of B-cells but is not expressed on stem cells nor on terminally-differentiated plasma cells.
Neg (nor) Regulation (regulator) of Localization (found) of membrane in stem cells
1) Confidence 0.04 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721296 Disease Relevance 0.87 Pain Relevance 0.28
It is generally accepted that the CD20 protein functions as a channel regulator of ion influx (Ernst et al 2005) and that this membrane-bound protein is specifically found on the membrane of B-cells but is not expressed on stem cells nor on terminally-differentiated plasma cells.
Neg (nor) Regulation (regulator) of Localization (found) of membrane-bound in stem cells
2) Confidence 0.04 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721296 Disease Relevance 0.86 Pain Relevance 0.28

General Comments

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