INT277811

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CD28, DCPS) mitochondrion (DCPS) nucleolus (DCPS)
nucleus (DCPS) plasma membrane (CD28) cytoplasm (DCPS)
Anatomy Link Frequency
T-cells 1
CD28 (Homo sapiens)
DCPS (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 1 41.44 Quite Low
fibrosis 2 23.84 Low Low
tolerance 8 5.00 Very Low Very Low Very Low
abatacept 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 1 54.64 Quite High
Death 8 36.00 Quite Low
Renal Disease 10 35.60 Quite Low
Nephrotoxicity 2 32.92 Quite Low
Injury 2 29.16 Quite Low
Fibrosis 2 23.84 Low Low
Hyalinosis 1 21.92 Low Low
Hypertension 5 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 5 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The costimulation signal is delivered when B7-1/CD80 and B7-2/CD86 on the surface of DCs engage CD28 on T-cells (Bromley et al 2001).
CD28 Binding (engage) of DCs in T-cells
1) Confidence 0.04 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0.05 Pain Relevance 0

General Comments

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