INT277985

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.36
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Epc1) extracellular space (Epo) aging (Epo)
extracellular region (Epo) nucleus (Epc1)
Anatomy Link Frequency
blood 1
Epo (Rattus norvegicus)
Epc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 16 98.44 Very High Very High Very High
Inflammation 22 67.52 Quite High
Pain 2 65.64 Quite High
aspirin 10 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 18 98.44 Very High Very High Very High
Myocardial Infarction 10 86.56 High High
Adhesions 14 71.76 Quite High
Atherosclerosis 70 68.52 Quite High
INFLAMMATION 30 67.52 Quite High
Syndrome 2 66.76 Quite High
Influenza Virus Infection 2 66.20 Quite High
Pain 2 65.64 Quite High
Hyperplasia 2 53.68 Quite High
Cardiovascular Disease 14 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the direct protective effect for myocytes (Hanlon et al 2005), EPO is able to increase EPC blood concentration in mice models of ischemia (Urao et al 2006).
EPO Positive_regulation (increase) of EPC in blood associated with ischemia
1) Confidence 0.03 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721378 Disease Relevance 0.74 Pain Relevance 0.18
Another substance to increase EPC number and function is erythropoietin (EPO).
EPO Positive_regulation (increase) of EPC
2) Confidence 0.02 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721378 Disease Relevance 0.63 Pain Relevance 0.19

General Comments

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