INT278316

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nlrp3)
Nlrp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 19 99.00 Very High Very High Very High
cytokine 18 98.08 Very High Very High Very High
chemokine 4 96.80 Very High Very High Very High
member 8 1 18.36 Low Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 99.00 Very High Very High Very High
Disease 9 89.20 High High
Apoptosis 14 87.28 High High
Insulin Resistance 3 80.16 Quite High
Diabetes Mellitus 4 78.32 Quite High
Cancer 5 46.08 Quite Low
Hypoxia 1 24.08 Low Low
Necrosis 1 16.88 Low Low
Leukemia 1 9.08 Low Low
Plasmodium Infection 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our studies provide the first evidence for a role of tyrosine kinase signaling molecules in NLRP3 activation.
Regulation (role) of Positive_regulation (activation) of NLRP3
1) Confidence 0.39 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Trx plays an important role in activation of the NLRP3 inflammasome responsible for activation of the cytokine interleukin 1?
Regulation (role) of Positive_regulation (activation) of NLRP3 associated with cytokine
2) Confidence 0.26 Published 2010 Journal Biol Trace Elem Res Section Body Doc Link PMC2855032 Disease Relevance 0.83 Pain Relevance 0.47

General Comments

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