INT278318

From wiki-pain
Revision as of 20:11, 24 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 12
Disease Relevance 4.24
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Hps5) cytoplasm (Hps5)
Hps5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 72 99.60 Very High Very High Very High
postherpetic neuralgia 78 97.44 Very High Very High Very High
chemokine 27 91.56 High High
cytokine 90 90.96 High High
Inflammatory response 36 87.60 High High
Pain 57 82.48 Quite High
Lasting pain 9 51.52 Quite High
Inflammatory mediators 18 43.12 Quite Low
Shingles 3 41.24 Quite Low
headache 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Zoster 456 100.00 Very High Very High Very High
INFLAMMATION 126 99.60 Very High Very High Very High
Disease 120 99.26 Very High Very High Very High
Post Operative Pain 78 97.44 Very High Very High Very High
Plasmodium Infection 153 91.28 High High
Chickenpox 6 91.08 High High
Pain 57 82.48 Quite High
Hypertension 9 81.60 Quite High
Fever 54 80.24 Quite High
Influenza Virus Infection 42 80.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, inhibition of ERK with Apigenin abrogated Hz-induced IL-1?
Gene_expression (abrogated) of Hz-induced
1) Confidence 0.37 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Altogether, these results reveal that Lyn/Syk activation following Hz exposure initiates the PI3K and ERK signaling pathways and these pathways appear to regulate the production of mature IL-1?.
Gene_expression (exposure) of Hz
2) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
production in Hz-mediated inflammatory cell recruitment using IL-1?
Gene_expression (production) of Hz associated with inflammation
3) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0.54 Pain Relevance 0.25
In our study, we have demonstrated that lipid rafts are involved in the Hz-induced signaling pathway and IL-1?
Gene_expression (pathway) of Hz-induced
4) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
These data indicate that our synthetic Hz preparation is high purity and free of contaminant.
Gene_expression (preparation) of Hz
5) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0.07 Pain Relevance 0.11
The ROS scavenger, N-acetylcysteine (NAC) inhibited both Hz- and MSU-induced IL-1?
Gene_expression (-) of Hz
6) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Thus far, we have shown that Hz-induced IL-1?
Gene_expression (shown) of Hz-induced
7) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0.64 Pain Relevance 0.20
In accordance with previous studies showing that HSP-90 stability [11] modulates inflammasome assembly, we found that Hz-induced IL-1?
Gene_expression (found) of Hz-induced
8) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0.06 Pain Relevance 0.08
To test whether the PI3K pathway is required for propagation of the Syk signaling pathway following Hz exposure, the PI3K inhibitor wortmannin was used prior to Hz stimulation.
Gene_expression (exposure) of Hz
9) Confidence 0.32 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Natural protection against HZ may occur by exogenous boosting (due to circulating VZV in the population) or endogenous boosting (through subclinical reactivation of latent VZV).
Gene_expression (protection) of HZ associated with herpes zoster
10) Confidence 0.05 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2928772 Disease Relevance 1.47 Pain Relevance 0.25
In the scenario describing the reduction of BOI, a reduction of QALY loss for the first 6 months in people with disease was included above the reduction in HZ cases (this is because the vaccine reduces disease severity in cases where HZ occurs in spite of vaccination).
Gene_expression (cases) of HZ associated with herpes zoster and disease
11) Confidence 0.04 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2928772 Disease Relevance 1.10 Pain Relevance 0.39
For HZ vaccination the prevented costs are distributed equally between hospital costs and prevented cost generated in the GP practice.
Gene_expression (vaccination) of HZ associated with herpes zoster
12) Confidence 0.04 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2928772 Disease Relevance 0.36 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox