INT279464

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.48
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Chkb) cytoplasm (Chkb)
Anatomy Link Frequency
muscle 1
Chkb (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 46 89.28 High High
ischemia 12 78.88 Quite High
Inflammatory response 6 68.44 Quite High
Inflammation 23 61.72 Quite High
antagonist 1 36.72 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 49 96.48 Very High Very High Very High
Fibrosis 56 94.72 High High
Coronary Artery Disease 16 79.52 Quite High
Apoptosis 3 79.32 Quite High
Frailty 6 75.92 Quite High
INFLAMMATION 29 68.08 Quite High
Cv Unclassified Under Development 11 65.28 Quite High
Reperfusion Injury 5 41.68 Quite Low
Cardiovascular Disorder Under Development 2 32.00 Quite Low
Injury 5 25.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, we did not observe significant changes in muscle histology; behavioral measurements, heart function or serum CK levels after arginine butyrate treatment.
Neg (not) Regulation (changes) of CK in muscle
1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888587 Disease Relevance 0.60 Pain Relevance 0.11
Our data regarding prednisone are consistent with the reports beneficial effects on serum CK levels in mdx mice [16].
Regulation (effects) of CK
2) Confidence 0.14 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888587 Disease Relevance 0 Pain Relevance 0
In 13 of the 16 patients who received thrombolytic therapy and C1-INH, the values of troponin T and creatine kinase-MB (CK-MB) were reduced by 36% and 57%, respectively, as compared to 18 control patients who had AMI and did not receive C1-INH therapy.
Regulation (values) of CK-MB associated with myocardial infarction
3) Confidence 0.00 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727911 Disease Relevance 0.88 Pain Relevance 0.10

General Comments

This test has worked.

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