INT279620

Context Info Confidence 0.18 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.99 Pain Relevance 0.40

plasma membrane (Grin2a, Grin2b) signal transduction (Grin2a) embryo development (Grin2b) locomotion (Grin2a)

Anatomy Link Frequency hippocampus 2 Grin2a (Rattus norvegicus) Grin2b (Rattus norvegicus)

Pain Link Frequency Relevance Heat Hippocampus 2 99.96 Spinal cord 2 87.84 Glutamate receptor 27 81.68 nMDA receptor 11 74.08 Dorsal horn 1 70.00 Neurotransmitter 1 52.60 Glutamate 14 51.00 anesthesia 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Diabetes Mellitus 87 99.84 Cognitive Disorder 1 85.84 Obesity 1 82.36 Ganglion Cysts 5 56.96 Retinal Diseases 1 56.08 Glaucoma 1 54.00 Retina Disease 1 52.96 Diabetic Retinopathy 9 35.36 Blindness 2 29.52 Hyperglycemia 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the hippocampus, immunoreactivity for NR2A and NR2B subunits are reduced in diabetic rats.

Negative_regulation (reduced) of NR2A Binding (immunoreactivity) of NR2B in hippocampus associated with diabetes mellitus and hippocampus

1) Confidence 0.18 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2728563 Disease Relevance 0.99 Pain Relevance 0.40

General Comments

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